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Cell Line References

Proven Performance

To find a reference, please select your cancer type from the drop down box below. The cell line reference tool will then display links to peer-reviewed publications and Harlan rodent models.

View Cell Line by Download Oncology brochure

  •  
    - Human Tissue
  •  
    - Rodent Tissue
  •  
    - Cancer Stem Cells (Human Tissue)
  •  

  •  
    - Patient-Derived Tumors (Human Tissue)
Hover over the reference to see the article that links to the peer-reviewed publication. Click on the rodent model to the right of the cell line to be taken to that model page on Harlan.com.
 Cell LineMiceRats
BladderKU-7 148149150151athymic nude 
T24 52 athymic nude
UM-UC1 278athymic nude 
UM-UC13 278athymic nude 
UM-UC3 278athymic nude 
Bladder (rat)NBT-II 299athymic nudeathymic nude
BrainA-172 198 athymic nude
G55 3 athymic nude
GL15 286C.B-17 SCID 
HTLA-230 5125athymic nude
SCID-beige
 
SH-SY5Y 2 athymic nude
U251 81202athymic nude 
U251 MG198199athymic nude 
U251-NG2 1285athymic nude 
U87ΔEGFR197athymic nude 
U87Fluc 7982athymic nude
BALB/c nude
 
U87 7181117173196athymic nude
NMRI nude
athymic nude
U87MG 4788083133134164195
198201205206209224249
athymic nude
BALB/c SCID
beige-nude-xid nude
CD-1 nude
NMRI nude
SCID
athymic nude
U87MG.wt EGFR 203athymic nude 
U87-TARTK 208NOD.SCID 
U138MG 203266athymic nude
NOD.SCID
 
U373 207 athymic nude
Brain (Rat Glioma)C6585978140180NOD.SCID
athymic nude
 
BrainBTSC83 200athymic nude 
LA-N-5 231athymic nude 
NGC-407-GFP 206 athymic nude
U87-SC 232athymic nude 
Brain(PDX) 271athymic nude 
BreastBT-474 616272143157160161162163
165211227228258270
athymic nude
BALB/c nude
SCID
SCID-beige
 
BT-474C 299athymic nudeathymic nude
BT474-EEI 252beige-nude-xid nude 
BT-474-M1 178253254257288beige-nude-xid nude
SCID
 
BT-474/TR 161162athymic nude 
HCC1569 162athymic nude 
JIMT-1 6869226289athymic nude
NMRI nude
SCID
 
KPL-4 143athymic nude
SCID-beige
 
MCF-7 8142497103128130131132138143146
192210217218219226229230255256290308309310311312313
athymic nude
BALB/c nude
CD-1 nude
MF1 nude
SCID
SCID-beige
athymic nude
MCF/HER2-18 160athymic nude 
MDA-MB-175 253beige-nude-xid nude 
MDA-MB-231 9111215567194111116
136139143156174176177184185186
187188189190191193209217267287299
athymic nude
BALB/c SCID
CD-1 nude
NOD.SCID
SCID
SCID-beige
athymic nude
MDA-MB-231-mCherry 282athymic nude 
MDA-MB-361 60256313athymic nude 
MDA-MB-435 12athymic nude 
MDA-MB-453 158256athymic nude 
MDA-MB-468 260266athymic nude
NOD.SCID
SCID
 
MEF-p95-HER2 64athymic nude 
MT-1 13170245athymic nude
CD-1 nude
athymic nude
T47D 67130210229259310313athymic nude
BALB/c nude
SCID-beige
 
ZR-75-1 299athymic nudeathymic nude
Breast2LMP (MDA-MB-231 subclone) 234NOD.SCID 
MCF-7 (CSC-like) 236athymic nude 
MCF-7 (mammospheres) 235athymic nude 
SUM159 234NOD.SCID 
BreastHBCX 1 270athymic nude 
HBCX 6 270athymic nude 
HBCX 7 270athymic nude 
HBCX 9 270athymic nude 
HBCX 12B 270athymic nude 
HBCX 17 270athymic nude 
TNBC (MC1) 273NOD.SCID 
MC1 274SCID-beige 
BMC-2147 274SCID-beige 
CervicalHeLa 78124athymic nude 
ME-180 291 athymic nude
SiHa 291 athymic nude
ColonBCS-TC2.2 113athymic nude 
Colo205 180299athymic nude
NOD.SCID
athymic nude
Colo320 113athymic nude 
Colo320-CD9 113athymic nude 
GEO 143258athymic nude
SCID-beige
 
HCA-7 17athymic nude 
LoVo 116299athymic nudeathymic nude
LS174T 63140159athymic nude 
MV522 180athymic nude
NOD.SCID
 
SW480 122SCID 
ColorectalCX-1 20athymic nude 
DLD-1 16152243294athymic nude 
HCT-116 171819112143153164athymic nude
SCID
SCID-beige
athymic nude
HT-29 162223114115116117
141143147239263295299
athymic nude
BALB/c nude
beige-nude-xid
NMRI nude
SCID-beige
 
SW620 243294athymic nude 
EndometrialECC-1 312athymic nude 
Embryo (murine)Src3T3 299athymic nudeathymic nude
EsophagealFLO-1 172athymic nude 
OE19 126127138154164athymic nude
BALB/c nude
MF1 nude
SCID
 
OE21 154athymic nude 
OE33 154155172athymic nude 
OE47 154athymic nude 
FibrosarcomaHT1080 77124209athymic nude
BALB/c SCID
 
GastricMKN45 124athymic nude 
N87 70143164175258athymic nude
NMRI nude
SCID
SCID-beige
 
Head & Neck Squamous Cell Carcinoma (HNSCC)Cal-27 656667athymic nude 
CCL 23 (HeLa contaminant) 67athymic nude 
FaDu 2165244athymic nude 
HNX-OE 21athymic nude 
SCC-1 284athymic nude 
UM-SCC1 6667116284athymic nude 
UMSCC38 279athymic nude 
WSUHN-31 60athymic nude 
LeukemiaARH-77 298C.B-17 SCID 
HEL9217 57C.B-17 SCID 
HL60 57171C.B-17 SCID 
HPB-ALL 27 athymic nude
K562 171C.B-17 SCID 
KG-1 144C.B-17 SCID 
MV4-11 166179180181182296athymic nude
NOD.SCID
 
TF1-α 57C.B-17 SCID 
THP-1 75C.B-17 SCID 
LiverAKH10 307SCID-beige 
Hep3B 25101119137222223225athymic nudeathymic nude
Hep-G2 122SCID 
HepT1 25 athymic nude
HuCCT1 262athymic nudeathymic nude
HuH6 26 athymic nude
Huh-7 122SCID 
KFJ6 307SCID-beige 
KFJ9 307SCID-beige 
KFJ10 307SCID-beige 
LiverAKH23 307SCID-beige 
KFJ18 307SCID-beige 
LungA549 9111533109110117
122143183244258
athymic nude
NMRI nude
SCID
SCID-beige
athymic nude
A549m 279athymic nude 
BEN 88SCID-beige 
Calu6 142143299athymic nude
NOD.SCID
SCID-beige
athymic nude
Colo-699 348889SCID-beige 
H226B 279athymic nude 
H1299 261athymic nude 
H358 31athymic nude 
KNS-62 348889SCID-beige 
L2987 143athymic nude
SCID-beige
 
LX-1 143athymic nude
SCID-beige
 
NCI-H460 114225293297athymic nude
C.B-17 SCID
athymic nude
NCI-H69 143athymic nude
SCID-beige
 
NCI-H82 118athymic nude 
NCI-N417 32athymic nude 
Lung (Murine)LL2 10athymic nude 
LungA549 108athymic nude 
H1299 108athymic nude 
Lung(NSCLC PDX) 272NOD.SCID 
LymphomaCA46 144SCID 
Grant 519 30144SCID 
Karpas 299 2890SCID 
L540cy 28SCID 
SP53 30SCID 
Z138 238SCID 
Lymphoma (non-Hodgkins)Raji 120121182NOD.SCID
SCID
 
Mammary (rat)DMBA-induced rat mammary carcinoma 301athymic nude 
Melanoma518A2 122247SCID 
607B 247SCID 
A375 163281306athymic nude 
A375M 249athymic nude 
DM6 85 athymic nude
Ge 248SCID-beige 
Mel-JUSO 247SCID 
NIH1286 84athymic nude 
SIT1 37SCID 
Melanoma (Murine)B16F10 3536250athymic nude
beige-nude-xid
 
MesotheliomaDEVy 100 athymic nude
Multiple MyelomaARP-1 144C.B-17 SCID 
KAS-6/1 76C.B-17 SCID 
L-363 120C.B-17 SCID 
LAGλ-1 7475athymic nude 
MM.1S 120144C.B-17 SCID 
NCI-H929 242NOD.SCID 
RPMI 8226 303304305C.B-17 SCID
SCID
 
U266 242NOD.SCID 
Oral686LN 279athymic nude 
KB (HeLa contaminant) 299athymic nudeathymic nude
Ovarian1A9 78athymic nude 
1A9ptx10 78athymic nude 
A2780 143athymic nude
SCID-beige
 
CAOV3 87athymic nude 
CD228 143athymic nude
SCID-beige
 
HEY 269athymic nude 
MW387 143athymic nude
SCID-beige
 
NMP-1 96athymic nude 
OVA-1 91SCID 
OVCAR-3 39739899athymic nude
NMRI nude
 
PA354 143athymic nude
SCID-beige
 
SKOV-3 38404155869293
95211212213214292
athymic nude
BALB/c nude
SCID
athymic nude
OvarianSKOV-3 (spherical cells) 213BALB/c nude 
Ovarian (rat)PROb 78athymic nude 
PancreaticAsPC-1 299athymic nudeathymic nude
BxPC-3 42275276athymic nude 
BxPC3/vector 276280athymic nude 
BxPC3/shSTAT3 280athymic nude 
Bx/shRON 276athymic nude 
CFPAC-1 43athymic nude 
Colo357 4244251athymic nude
SCID-beige
 
HPAC 299athymic nudeathymic nude
L3.6pl 123236athymic nude 
MIA-Luc 202athymic nude 
MIA PaCa-2 54167277athymic nude 
PANC-1 42167168athymic nude 
Panc185 272athymic nude 
Panc89 45SCID 
Panc430 262SCID 
PL45 43athymic nude 
T3M4 42athymic nude 
PancreaticJH033 272athymic nude 
ProstateCWR22 51143athymic nude
SCID-beige
 
DU-145 29211221athymic nude
ICR-SCID
 
LAPC4 107athymic nude 
LNCaP 50104105106194223246athymic nude
SCID
 
LuCap35 143athymic nude
SCID-beige
 
MDA-PCa-2b 143athymic nude
SCID-beige
 
PC-3 46474849129135138143
169209211216220240246283302
athymic nude
BALB/c nude
BALB/c SCID
MF1 nude
SCID
SCID-beige
 
PC-3M 164athymic nude 
VCaP 215athymic nude 
ProstateDU-145 (spheroid cells) 233NOD.SCID 
Renal786O 127138180athymic nude
BALB/c nude
MF1 nude
NOD.SCID
 
RetinoblastomaY79 241athymic nude 
Skin(HPV16)BC-1-Ep/SL-LF 314athymic nude
beige-nude-xid

SHrN ("Shorn")
 
Skin (benign)Shope papilloma 301athymic nude 
Squamous-Cell/Epidermoid CarcinomaA431 143211262264265266267268athymic nude
NOD.SCID
SCID-beige
 
TesticularNCCIT 53athymic nude 
Uveal melanomaM619 102SCID 
MUM2B 102SCID 
OCM1a 102SCID 
VulvaSK-LMS-1 145 athymic nude

Many factors can influence your selection of an appropriate research model. These published studies are identified to assist you in your selection. Harlan Laboratories does not guarantee model performance in research studies.

The cell line abbreviation “(PDX)” is utilized as generic naming convention of a “Patient-derived Xenograft” in absence of a formal name by the researcher(s).

References

  1. Verhoef, J.J.C. et al., Radiat Oncol, 2, 38 (2007). Netherlands (athymic nude mice)
  2. Ponthan, F. et al., Oncol Reports, 10, 1587 (2003). Netherlands (athymic nude rats)
  3. Rubenstein, J.L. et al., Neoplasia, 2(4), 306 (2000). North America (athymic nude rats)
  4. Plunkett, R.J. et al., J Neurosurg, 90, 1071 (1999). North America (athymic nude rats)
  5. Brignole, C. et al., J Natl Cancer Inst, 96, 1171 (2004). Italy (athymic nude mice, SCID-beige mice)
  6. Pan, Y. et al., Breast Cancer Res, 8, R63 (2006). North America (athymic nude mice)
  7. Sartorius, C.A. et al., Cancer Res, 65(21), 9779 (2005). North America (athymic nude mice)
  8. Arteaga, C.L. et al., Cell Growth & Diff, 4, 193 (1993). North America (athymic nude mice)
  9. Hardman, E.W. et al., Cancer Cell Intl, 2, 10 (2002). North America (athymic nude mice)
  10. Amiekhosravi, A. et al., Thromb Haemost, 90, 549 (2003). North America (athymic nude mice)
  11. Dikmen, Z.G. et al., Turk J Med Sci, 35, 65 (2005). North America (athymic nude mice)
  12. Richert, M.M. et al., Breast Cancer Res, 7, R819 (2005). North America (athymic nude mice)
  13. Burch, S. et al., J Biomedical Optics, 10, 034011-1-13 (2005). North America (athymic nude rats)
  14. Blask, D.E. et al., Breast Cancer Res, And Treatment 79, 313 (2003). North America (athymic nude rats)
  15. Bäuerle, T. et al., Intl J Oncol, 28, 573 (2006). Germany (athymic nude rats)
  16. Prewett, M.C. et al., Clin Cancer Res, 8, 994 (2002). North America (athymic nude mice)
  17. Sheng, H. et al., J Clin Invest, 99, 2254 (1997). North America (athymic nude mice)
  18. Yang, M. et al., Proc Nat Acad Sci, 102, 6027 (2005). North America (athymic nude mice)
  19. Park, B.H. et al., Proc Natl Acad Sci, 98, 2598 (2001). North America (athymic nude mice)
  20. Kruskal, J.B. et al., Radiology, 215, 852 (2000). North America (athymic nude mice)
  21. Tijink, B.M. et al., J Nucl Med, 47, 1127 (2006). EU (athymic nude mice)
  22. Marchal, F. et al., Oncology Reports, 14, 1203 (2005). France (athymic nude rats)
  23. Wang, M. et al., World J Gastroenterol, 9(11), 2627 (2003). France (athymic nude rats)
  24. Dauchy, R. T. et al., Cancer Letters, 209, 7 (2004). North America (athymic nude rats)
  25. Svechnikova, I. et al., Intl J Oncol, 22, 579 (2003). Netherlands (athymic nude rats)
  26. Till, H. et al., Surgical Endoscopy, 19, 1483 (2005). Germany (athymic nude rats)
  27. Barone, T.A. et al., Blood, 90, 298 (1997). North America (athymic nude rats)
  28. Francisco, J.A. et al., Blood, 102, 1458 (2003). North America (SCID mice)
  29. Geldhof, A.B. et al., Clin & Experimental Metastasis, 16(5), 447 (1998). North America (ICR-SCID mice)
  30. Wang, M. et al., Blood, 109, 5455 (2007). North America (SCID mice)
  31. Zou, Y. et al., J Natl Cancer Inst, 90, 1130 (1998). North America (athymic nude mice)
  32. Maneckjee, R. and Minna, J.D., Proc Natl Acad Sci, 89, 1169 (1992). North America (athymic nude mice)
  33. Weinberg, O.K. et al., Cancer Res, 65, 11287 (2005). North America (athymic nude mice)
  34. Boehle, A.S. et al., Intl J Cancer, 94, 420 (2001). Germany (SCID-beige mice)
  35. Horton, H.M. et al., Proc Natl Acad Sci, 96, 1553 (1999). North America (athymic nude mice, beige-nude-xid mice)
  36. Malafa, M.P. et al., Annals of Surgical Oncol, 9(10), 1023 (2002). North America (athymic nude mice)
  37. Bromberg, M.E. et al., Proc Natl Acad Sci, USA 92, 8205 (1995). North America (SCID mice)
  38. Modesitt, S.C. et al., Clin Cancer Res, 7,1487 (2001). North America (athymic nude mice)
  39. Duyndam, M.C.A. et al., Am J Pathol, 160, 537 (2002). Netherlands (athymic nude mice)
  40. Gossmann, A. et al., J Obstetrics and Gynecol, 183, 956 (2000). North America (athymic nude rats)
  41. Mahasreshti, P.J. et al., Clin Cancer Res, 7, 2057 (2001). North America (SCID mice)
  42. Fukasawa, M. and Murray, K., Clin Cancer Res, 10, 3327 (2004). North America (athymic nude mice)
  43. Koehler, J.A. and Drucker, D.J., Diabetes, 55, 1369 (2006). North America (athymic nude mice)
  44. Weber, D. et al., Cancer Res, 60, 5284 (2000). North America (athymic nude mice)
  45. Boenicke, L. et al., J Mol Med, 81, 205 (2003). Germany (SCID mice)
  46. Zhang, X. et al., J Nucl Med, 47, 492 (2006). North America (athymic nude mice)
  47. Tuomela, J.M. et al., BMC Cancer, 8, 81 (2008). Germany (athymic nude mice)
  48. Srivastava, S.K. et al., Carcinogenesis, 24(10), 1665 (2003). North America (athymic nude mice)
  49. Hillman, G.G. et al., Mol Cancer Ther, 3, 1271 (2004). North America (athymic nude mice)
  50. Graff, J.R. et al., J Biol Chem, 275, 24500 (2000). North America (athymic nude mice)
  51. Gregory, C.W. et al., Cancer Res, 61, 2892 (2001). North America (athymic nude mice)
  52. Cabrera, G. et al., Mol Cancer, 5, 32 doi:10.1186/1476-4598-5-32 (2006). North America (athymic nude rats)
  53. Adkins, H.B. et al., J Clin Invest, 112, 575 (2003). North America (athymic nude mice)
  54. Weydert, C. et al., Mol Cancer Ther, 2, 361 (2003). North America (athymic nude mice)
  55. Fu, X, Tao, L and Zhang, X., Cancer Gene Therapy, 14, 480 (2007). North America (athymic nude mice)
  56. Sun, L. and Chen, C., J Biol Chem, 272(40), 25367 (1997). North America (athymic nude mice)
  57. Sutherland, M.K. et al., mAbs 1(5), 481 (2009). North America (C.B-17 SCID mice)
  58. Lai, C.P.K. et al., Cancer Res, 67(4), 1545 (2007). North America (athymic nude mice)
  59. Folkins, C. et al., Cancer Res, 69(18), 7243 (2009). North America (athymic nude mice)
  60. Ueno, N.T. et al., Cancer Res, 62, 6712 (2002). North America (athymic nude mice)
  61. Nagata, Y. et al., Cancer Cell, 6, 117 (2004). North America (athymic nude mice)
  62. Puig, T. et al., Clin. Cancer Res., 15, 7608 (2009). UK (athymic nude mice)
  63. Liu, Z. et al., Nano Res, 3(3), 222 (2010). North America (athymic nude mice)
  64. Chandarlapaty, S. et al., Oncogene, 29, 325 (2010). EU (athymic nude mice)
  65. Simons, A.L. et al., Int J Radiat Oncol Biol Phys, 69(4), 1222 (2007). North America (athymic nude mice)
  66. Want, D. et al., Clin Cancer Res, 14(19), 6228 (2008). North America (athymic nude mice)
  67. LoTempio, M.M. et al., Clin Cancer Res, 11(19), 6994 (2005). North America (athymic nude mice)
  68. Barok, M. et al., Mol Cancer Ther, 6(7), 2065 (2007). Netherlands (NMRI nude mice, SCID mice)
  69. Tanner, M. et al., Mol Cancer Ther, 3(12), 1585 (2004). Netherlands (NMRI nude mice)
  70. Tanner, M. et al., Annals of Oncol, 16, 273 (2005). Netherlands (NMRI nude mice)
  71. Lin, L. et al., Neoplasia, 12(1), 39 (2010). North America (athymic nude mice)
  72. Moulder, S.L. et al., Cancer Res, 61, 8887 (2001). North America (athymic nude mice)
  73. Zhang, X. et al., Clin Cancer Res, 11, 323 (2005). North America (athymic nude mice)
  74. Campbell, R.A. et al., Int J Oncol, 28(6), 1409 (2006). North America (athymic nude mice)
  75. Chen, H. et al., Blood, 113, 1992 (2009). North America (athymic nude mice)
  76. Dingli, D. et al., Clin Cancer Res, 8, 3948 (2002). North America (C.B-17 SCID mice)
  77. Chavez-Blanco, A. et al., Cancer Cell Int, 6, 2 (2006). North America (athymic nude mice)
  78. Ferretti, S. et al., Neoplasia, 11(9), 874 (2009). EU (athymic nude mice)
  79. Heikkilä, J.E. et al., PLoS ONE, 5(1), e8603 (2010). UK (BALB/c nude mice)
  80. Xiao, W. et al., Eur J Nucl Med Mol Imaging, 36, 94 (2009). North America (athymic nude mice)
  81. Li, L. et al., Clin Cancer Res, 13(7), 2178 (2007). North America (athymic nude mice)
  82. Hsu, A.R. et al., J Nucl Med, 48, 445 (2007). North America (athymic nude mice)
  83. Chen, X. et al., J Nucl Med, 45, 1776 (2004). North America (athymic nude mice)
  84. Menon, C. et al., Am J Physiol Heart Circ Physiol, 24, H317 (2003). North America (athymic nude mice)
  85. Ueno, T. et al., Mol Cancer Ther, 5(3), 732 (2006). North America (athymic nude rats)
  86. Goyeneche, A.A. et al., Clin Cancer Res, 13(11), 3370 (2007). North America (athymic nude mice)
  87. Li, D. et al., Oncogene, 21, 2805 (2002). North America (athymic nude mice)
  88. Boehle, A.S. et al., Ann Thorac Surg, 69, 1010 (2000). Germany (SCID-beige mice)
  89. Kurdow, R. et al., Ann Thorac Surg, 73, 905 (2002). Germany (SCID-beige mice)
  90. Hamblett, K.J. et al., Clin Cancer Res, 10, 7063 (2004). North America (SCID mice)
  91. Santin, A.D. et al., Cancer Res, 65(10), 4334 (2005). North America (SCID mice)
  92. Nilsson, M.B. et al., J Biol Chem, 282(41), 29919 (2007). North America (SCID mice)
  93. Spaeth, E.L. et al., PloS ONE, 4(4), e4992 (2009). North America (SCID mice)
  94. Bruckheimer, E.M. et al., Neoplasia, 11(6), 509 (2009). North America (SCID mice, NOD.SCID mice)
  95. Nagengast, W.B. et al., J Nucl Med, 48, 1313 (2007). Netherlands (athymic nude mice)
  96. Auzenne, E. et al., Neoplasia, 9(6), 479 (2007). North America (athymic nude mice)
  97. Rodrigues-Ferreira, S. et al., PLoS ONE, 4(10), e7239 (2009). UK (SCID mice)
  98. Houba, P.H.J. et al., British J Cancer, 78(12), 1600 (1998). Netherlands (athymic nude mice)
  99. Vingerhoeds, M.H. et al., British J Cancer, 74, 1023 (1996). Netherlands (NMRI nude mice)
  100. Le Pimpec-Barthes, F. et al., British J Cancer, 81(8), 1344 (1999). EU (athymic nude rats)
  101. Fu, X. et al., Mol Ther, 7(6), 748 (2003). North America (athymic nude mice)
  102. Folberg, R. et al., Invest Ophthalmol Vis Sci, 48(7), 2967 (2007). North America (SCID mice)
  103. Swami S., et.al., Horm Cancer. 2011 June 1; 2(3): 190–202. North America (athymic nude mice)
  104. Kiyama, S. et al., Cancer Res, 63, 3575 (2003). North America (athymic nude mice)
  105. Elsadek, B. et al., Prostate Cancer and Prostatic Diseases, 14, 14 (2011). Germany (SCID mice)
  106. Sun, S. et al., J Clin Invest, 120(8), 2715 (2010). North America (athymic nude mice)
  107. Li, T.H. et al., Nucleic Acids Res, 35(8), 2767 (2007). North America (athymic nude mice)
  108. Pan, J. et al., PLoS ONE, 5(10), e13298. doi:10.1371/journal.pone.0013298 (2010). North America (athymic nude mice)
  109. Määttä, A.-M. et al., Int J Cancer, 121, 863 (2007). Netherlands (NMRI nude mice)
  110. Jarzynka, M.J. et al., Int J Oncol, 28(2), 337 (2006). North America (athymic nude mice)
  111. Bruckheimer, E.M. et al., Neoplasia, 11(6), 509 (2009). North America (athymic nude mice, SCID mice, NOD.SCID mice)
  112. Yi, J. M. et al., Cancer Res, 68(19), 8094 (2008). North America (SCID mice)
  113. Ovalle, S. et al., Int J Cancer, 121, 2140 (2007). Spain (athymic nude mice)
  114. Schleup, T. et al., Clin Cancer Res, 15, 181 (2009). North America (athymic nude mice)
  115. Orian-Rousseau, V. et al., Int J Cancer, 113, 699 (2005). Germany (SCID-beige mice)
  116. Zielske, S.P. et al., Int J Radiat Oncol Biol Phys, 75(3), 843 (2009). North America (athymic nude mice)
  117. Kaafarani, I. et al., FASEBJ, 23, doi: 10.1096/fj.08-127852 (2009). France (NMRI nude mice)
  118. Koskimaki, J. E. et al., BMC Cancer, 10, 29 (2010). North America (athymic nude mice)
  119. Jakubezak, J.L. et al., Cancer Res, 63, 1490 (2003). North America (athymic nude mice)
  120. McEarchern, J.A. et al., Clin Cancer Res, 14, 7763 (2008). North America (C.B-17 SCID mice)
  121. Kelley, S.K. et al., Br J Pharmacol, 148(8), 1116 (2006). North America (SCID mice)
  122. Smrekar, B. et al., Gene Therapy, 10, 1079 (2003). UK; Germany (A/J mice)
  123. Tremmel, M. et al., Blood, 114(25), 5236 (2009). Germany (athymic nude mice)
  124. Cuesta, Á.M., et al., PLoS ONE, 4(4), e5381. doi:10.1371/journal.pone.0005381 (2009). Spain (athymic nude mice)
  125. Pastorino, F. et al., Cancer Res, 63, 86 (2003). Italy (athymic nude mice)
  126. Kelly, P. et al., British J Cancer, 103, 232 (2010). UK (SCID mice)
  127. Larkin, J.O. et al., Ultrasound Med Biol, 34(3), 406 (2008). UK (MF1 nude mice)
  128. Kang, K.S., et al., PLoS ONE 5(4): e10296. doi:10.1371/journal.pone.0010296 (2010). North America (athymic nude mice)
  129. Shah, G.V. et al., Endocrine-Related Cancer, 15, 953 (2008). North America (athymic nude mice)
  130. Lipnik, K. et al., Virol, 349, 121 (2006). Germany (SCID-beige mice)
  131. Agu, C.A. et al., J Gene Med, 8, 229 (2006). Germany (SCID-beige mice)
  132. Rhodes, L.V. et al., Breast Cancer Res Treat, 121(2), 293 (2010). North America (SCID-beige mice)
  133. Barone, T.A. et al., J Neuro-Oncol, 95(1), 37 (2009). North America (athymic nude rats)
  134. Nanda, D. et al., Cancer Res, 61, 8743 (2001). UK (beige-nude-xid mice)
  135. Markaverich, B. et al., Eviron Health Perspect,110, 169 (2002). North America (athymic nude mice)
  136. Stan, S.D. et al., Cancer Res, 68(18), 7661 (2008). North America (athymic nude mice)
  137. Shashkova, E.V. et al., Cancer Res, 68, 5896 (2008). North America (athymic nude mice)
  138. Larkin, J.O. et al., Ann Surg, 245(3), 469 (2007). UK (BALB/c nude mice, MF1 nude mice)
  139. Loebinger, M.R. et al., Cancer Res, 69(23), 8862 (2009). UK (NOD.SCID mice)
  140. Cai, W. et al., J Nucl Med, 48, 304 (2007). North America (athymic nude mice)
  141. Squires, M.S. et al., Mol Cancer, 8(2), 324 (2009). UK (BALB/c nude mice)
  142. Airoldi, I. et al., PLoS ONE, 4(7), e6119. doi:10.1371/journal.pone.0006119 (2009). Italy (NOD.SCID mice)
  143. Lee, F.Y.F. et al., Cancer Chemother Pharmacol, 63, 201 (2009). North America (athymic nude mice, SCID-beige mice)
  144. Yang, J. et al. Cancer Cell, 10, 295 (2006). North America (SCID mice)
  145. Dauchy, R.T. et al., J Pineal Res, 47, 32 (2009). North America (athymic nude rat)
  146. Wu, J. et al., Cancer Res, 71, 2622 (2011). North America (athymic nude rat)
  147. Sharma, S. et al. Ejc Supplements, ISSN:13596349, 8(7), 66 (2010). North America (athymic nude mice)
  148. Hadaschik, B.A. et al. Cancer Res, 68, 4506 (2008). North America (athymic nude mice)
  149. Chadalapaka, G. et al, Cancer Res, 68(13), 5345 (2008). North America (athymic nude mice)
  150. Cho, S.D. et al., Mol Pharmacol, 77(3), 396 (2010). North America (athymic nude mice)
  151. Jutooru, I. et al. Exp Cell Res, 316(13), 2174 (2010). North America (athymic nude mice)
  152. Zawel, L. et al. PNAS, 99(5), 2848 (2002). North America (athymic nude mice)
  153. Donawho, C.K. et al. Clin Cancer Res, 13(9), 2728 (2007). North America (athymic nude mice)
  154. Rockett, J.C. et al., Br J Cancer, 75(2), 258 (1997). UK (athymic nude mice)
  155. Kan, T. et al., Gastroenterol, 136(5), 1689 (2009) North America (athymic nude mice)
  156. Zhang, S. et al. Mol Cancer Ther, 11, 108 (2012). North America (athymic nude mice)
  157. Zhang, K.-X. et al., Breast Cancer Res Treat, 125, 89 (2011). North America (athymic nude mice)
  158. Zhang, K.-X. et al., Breast Cancer Res Treat, 125, 89 (2011). North America (athymic nude mice)
  159. Liu, Z. et al., Nano Res, 3, 222 (2010). North America (athymic nude mice)
  160. Rimawi, M.R. et al., Clin Cancer Res, 17, 1351 (2011). North America (athymic nude mice)
  161. Zhao, Y. et al., Cancer Res, 71, 4585 (2011). North America (athymic nude mice)
  162. Scaltriti, M. et al., Mol Cancer Ther, 10, 817 (2011). North America (athymic nude mice)
  163. Massey, A.J. et al., Mol Cancer Ther, 9, 906 (2010). Switzerland (athymic nude mice)
  164. Maira, S.-M. et al., Mol Cancer Ther, doi:10.1158/1535-7163.MCT-11-0474. Switzerland (athymic nude mice)
  165. O'Donovan, N. et al., Invest New Drugs, 29, 752 (2011). UK (BALB/c nude mice)
  166. Chao, O. et al., J Med Chem, 52, 7808 (2009). North America (athymic nude mice)
  167. Yu, Y.A. et al., Mol Cancer Ther, 8, 141 (2009). North America (athymic nude mice)
  168. Haddad, D. et al., J Translational Med, 9, 36 (2011). North America (athymic nude mice)
  169. Gourdeau, H. et al., Cancer Chemother Pharmacol, 61, 911 (2008). North America (athymic nude mice)
  170. Liu, T.W. et al., Bioconjugate Chem, 22, 1021 (2011). North America (athymic nude mice, athymic nude rats)
  171. Alzani, R. et al., Exp Hematol, 38, 259 (2010). Italy (C.B-17 SCID mice)
  172. Sehdev, V. et al., Mol Cancer Ther, doi: 10.1158/1535-7163.MCT-11-0623 (2012). North America (athymic nude mice)
  173. Bralten, L.B.C. et al., Ann Neurol, 69, 455 (2011). Netherlands (SCID mice)
  174. Ayuzawa, R. et al., Cancer Letters,280, 31 (2009). North America (SCID mice)
  175. Barok, M. et al., Cancer Letters, 306, 171 (2011). Netherlands (SCID mice)
  176. Zeng, Q. et al., Euro J Cancer, 46, 1132 (2010). North America (athymic nude mice)
  177. Pais, A. et al. Cancer Res, 71(24), 7387 (2011). Israel (SCID mice)
  178. Junttila, T.T. et al., Cancer Cell, 15, 429 (2009). North America (SCID mice)
  179. Daigle, S. R. et al., Cancer Cell, 20, 53 (2011). North America (athymic nude mice)
  180. Patyna, S. et al. Mol Cancer Ther, 5, 1774 (2006). North America (athymic nude mice, NOD.SCID mice)
  181. Zarrinkar, P.P. et al. Blood, 114(14), 2984 (2009). North America (NOD.SCID mice)
  182. Mertz, J.A. et al., PNAS, 108(40), 16669 (2011). North America (athymic nude mice)
  183. Tokalov, S.V. et al., J Biomed and Biotechnol, Article ID 580531, 4 pdoi:10.1155/2010/580531 (2010). Germany (athymic nude rats)
  184. Anastas, J.N. et al., Oncogene, doi:10.1038/onc.2011.528 (2011). North America (athymic nude mice)
  185. Mitra, A. et al., Breast Cancer Res, 10:R22 (2008). North America (athymic nude mice)
  186. Volk, L.D. et al., Neoplasia, 10(6), 613 (2008). North America (athymic nude mice)
  187. Hiraga, T. et al., Cancer Res, 61, 4418 (2001). North America (athymic nude mice)
  188. Mukhopadhyay, K.D. et al., PLoS ONE, 6(6), e20473 (2011). North America (athymic nude mice)
  189. Bandyopadhyay, A. et al., PLoS ONE, 5(4), e10365 (2010). North America (athymic nude mice)
  190. Walsh, C. et al., Cancer Biol Ther, 9(10), 778 (2010). North America (athymic nude mice, BALB/c SCID mice)
  191. Lee, S.-M. et al., ACS Nano, 4(9), 4971 (2010). North America (athymic nude mice)
  192. Kerjaschki, D. et al. J Clin Invest, 121(5), 2000 (2011). Germany (SCID mice)
  193. Whitehurst, B. et al., Int J Cancer, 121, 2181 (2007). North America (SCID mice)
  194. Graeser, R. et al., Int J Cancer, 122, 1145 (2008). Germany (SCID mice)
  195. Gomez-Manzano, C. et al., Neuro-Oncol, 10, 940 (2008). North America (athymic nude mice)
  196. Heinkelein, M. et al., Cancer Gene Ther, 12, 947 (2005). Germany (athymic nude mice)
  197. Verheije, M.H. et al., J Virol, 83(15), 7507 (2009). Netherlands (athymic nude mice)
  198. Ke, L.D. et al., Clin Cancer Res, 6, 2562 (2000). North America (athymic nude mice)
  199. Clark, A.J. et al., J Neurosurg, 112, 18 (2010). North America (athymic nude mice)
  200. Calzolari, A. et al., Transl Oncol, 3(2), 123 (2010). Italy (athymic nude mice)
  201. Schiappacassi, M. et al., Mol Cancer Ther, 7(5), 1164 (2008). Italy (athymic nude mice)
  202. Yoon, H. et al., J Cellular Biochem, 108, 832 (2009). North America (athymic nude mice)
  203. Abourbeh, G. et al., Nucl Med and Biol, 34, 55 (2007). Israel (athymic nude mice)
  204. Benny, O. et al., FASEB J, 22, 488 (2008). Israel (CD-1 nude mice)
  205. Yin, S. et al., Neuro-Oncol, 12(1), 19 (2010). Sweden (athymic nude rats, SCID mice)
  206. Khan, Z. et al., Neuro-Oncol, 12(6), 549 Sweden (athymic nude rats)
  207. Buursma, A.R. et al., J Nucl Med, 46, 2068 (2005). Netherlands (athymic nude rats)
  208. Gunasekaran, K. et al., J Biol Chem, 285(25), 19637 (2010). North America (NOD.SCID mice)
  209. Li, J.-L. et al., Cancer Res, 67(23), 11244 (2007). Germany (BALB/c SCID mice)
  210. Holen I., et.al., Breast Cancer Research 2012, 14:R86. United Kingdom (BALB/c nude mice)
  211. Hennessy, B.T. et al. Clin Cancer Res, 13(24), 7421 (2007). North America (athymic nude mice)
  212. Nakamori, M. et al., Clin Cancer Res, 9, 2727 (2003). North America (athymic nude mice)
  213. Ma, L. et al., Acta Biochim Biophys Sin, 42(9), 593 (2010). Asia (BALB/c nude mice)
  214. Shao, M. et al., Cancer Res, 69, 9192 (2009). North America (BALB/c nude mice)
  215. Lljin, K. et al., Clin Cancer Res, 15(19), 6070 (2009). Finland (athymic nude mice)
  216. Izhak, L. et al., J Immunol, 183, 732 (2009). Israel (SCID-beige mice)
  217. Inbar-Rozensal, D. et al., Breast Cancer Res, 11, R78 (2009). Israel (CD-1 nude mice)
  218. González, L. et al., J Biol Chem, 281(30), 20851 (2006). Spain (athymic nude mice)
  219. Wu, L. et al., Clin Cancer Res, 11(22), 8195 (2005). North America (athymic nude mice)
  220. Ghosh, A.K. et al., Cancer Res, 56(3), 718 (2005). North America (athymic nude mice)
  221. Tang, L. et al., J Nutr, 135, 287 (2005). North America (athymic nude mice)
  222. Fu, X. et al., Gene Ther, 10, 1458 (2003). North America (athymic nude mice)
  223. Shashkova, E.V. et al., Cancer Res, 68(14), 5896 (2008). North America (athymic nude mice)
  224. Ozawa, T. et al., Mol Pharmaceutics, 1(5), 368 (2004). North America (athymic nude rats)
  225. Bristol, J.A. et al., Mol Ther, 7(6), 755 (2003). North America (athymic nude mice)
  226. Folgiero, V. et al., Cell Death and Disease, 3, e440; doi:10.1038/cddis.2012.179 (2012). Italy (athymic nude mice, SCID mice)
  227. Jensen, M.R. et al., Breast Cancer Res, 10, R33 (2008). Switzerland (athymic nude mice)
  228. Golubovskaya, V.M. et al., J Med Chem, 51(23), 7405 (2008). North America (athymic nude mice)
  229. Hernandez-Alcoceba, R. et al., Human Gene Ther, 11, 2009 (2000). North America (athymic nude mice)
  230. Gutierrez, M.C. et al., JCO, 23(11), 2469 (2005). UK (athymic nude mice)
  231. Mahller, Y.Y. et al. PLoS ONE, 4(1):e4235. doi:10.1371/journal.pone.0004235 (2009). North America (athymic nude mice)
  232. Zhou, Y. et al., J Biol Chem, 286, 32843 (2011). North America (athymic nude mice)
  233. Salvatori, L. et al., PLoS ONE, 7(2), e31467. doi:10.1371/journal.pone.0031467 (2012). Italy (NOD.SCID mice)
  234. Londoño-Joshi, A.I. et al., Breast Cancer Res Treat, DOI 10.1007/s10549-011-1763-0 (2011). North America (NOD.SCID mice)
  235. Joseph, I. et al., Cancer Res, 70, 9494 (2010). North America (athymic nude mice)
  236. Lonardo, E. et al., Cell Stem Cell, 9(5), 433 (2011). Spain (athymic nude mice)
  237. Xiao, K. et al., Biomaterials, 30(30), 6006 (2009). North America (athymic nude mice)
  238. Li, Y. et al., J Immunol, 179, 4263 (2007). North America (SCID mice)
  239. Kumagai, T. et al., J Natl Cancer Inst, 95(12), 896 (2003). North America (beige-nude-xid mice)
  240. Kumagai, T. et al., Clin Cancer Res, 10, 1508 (2004). North America (beige-nude-xid mice)
  241. Audo, I. et al., Invest Ophthalmol Vis Sci, 44, 4192 (2003). North America (athymic nude mice)
  242. Cocco, C. et al., Clin Cancer Res, 16, 4188 (2010). Italy (NOD.SCID mice)
  243. Ayers, G.D. et al., J Ultrasound Med, 29(6), 891 (2010). North America (athymic nude mice)
  244. Ning, S. et al., Cancer Res, 70(19), OF1 (2010). North America (athymic nude rats)
  245. Yee, A.J.M. et al., Breast Cancer Res, 9(4), R47 (2007). North America (CD-1 nude mice, athymic nude rats )
  246. Mercatelli, N. et al., PLoS ONE, 3(12), e4029 (2008). Italy (SCID mice)
  247. Thallinger, C. et al., J Invest Dermatol, 127, 2411 (2007). Germany (SCID mice)
  248. Elsner, L. et al., J Immunol, 179, 5523 (2007). Germany (SCID-beige mice)
  249. Ren, G. et al., J Nucl Med, 50, 1692 (2009). North America (athymic nude mice)
  250. Morello, S. et al., Neoplasia, 13(4), 365 (2011). Italy (athymic nude mice)
  251. Stangl, S. et al., J Immunol, 176, 6270 (2006). Germany (SCID-beige mice)
  252. Phillips, G.D.L. et al., Cancer Res, 68, 9280 (2008). North America (beige-nude-xid mice)
  253. Lee-Hoeflich, S.T. et al., Cancer Res, 68, 5878 (2008). North America (beige-nude-xid mice)
  254. Yao, E. et al., Clin Cancer Res, 15, 4147 (2009). North America (beige-nude-xid mice)
  255. Allegrucci, C. et al., Mol Cancer, 10, 7 (2011). UK (MF1 nude mice)
  256. Brachmann, S.M. et al., PNAS, 106(52), 22299 (2009). North America (athymic nude mice)
  257. Hoeflich, K.P. et al., Clin Cancer Res, 15(14), 4649 (2009). North America (beige-nude-xid mice)
  258. Wong, T.W. et al., Clin Cancer Res, 12(20), 6186 (2006). North America (athymic nude mice)
  259. Halasi, M. et al., Cell Cycle, 9(4), 1214 (2010). North America (athymic nude mice)
  260. Zhang, S. et al., Endocrine-Related Cancer, 16, 835 (2009). North America (athymic nude mice)
  261. Hitosugi, T. et al., Mol Cell, 44(6), 864 (2011). North America (athymic nude mice)
  262. Jimeno, A. et al., Cancer Res, 65, 3003 (2005). North America (athymic nude mice)
  263. Mutsaers, A.J. et al., Clin Cancer Res, 15, 2397 (2009). North America (athymic nude mice)
  264. Guix, M. et al., J Clin Invest, 118(7), 2609 (2008). North America (athymic nude mice)
  265. Donnini, S. et al., Oncogene, doi:10.1038/onc.2011.503 (2011). Italy (athymic nude mice)
  266. Shir, A. et al., Clin Cancer Res, 17, 1033 (2011). Israel (NOD.SCID mice)
  267. Lee, C.M. et al., BMC Cancer, 10, 255 (2010). North America (athymic nude mice)
  268. Alameda, J.P. et al., Cell Death and Disease, 2, e208; doi:10.1038/cddis.2011.82 (2011). Spain (athymic nude mice)
  269. Valle BL, et al,. PLoS ONE 8(4): e61836 (2013). North America (Athymic nude mice).
  270. Zhang C.C, et.al., Clinical Cancer Research 1-12; 2012. AACR. France (athymic nude mice)
  271. Carlson B. L, et.al., Curr Protoc Pharmocol. 2011 Mar; Chapter 14: Unit 14. 16. North America (athymic nude mice)
  272. Calles A., et.al., Curr Protoc Pharmacol. 2013 Jun; Chapter 14: Unit 14.26. North America (NOD.SCID mice, athymic nude mice)
  273. Litzenburger BC., et.al., Clin Cancer Res April 15, 2011. 17; 2314. North America (NOD.SCID mice)
  274. Schott AF, et.al., Clin Cancer Res clincanres.3326.2012; Published Online First January 22, 2013. North America (SCID-beige mice)
  275. Leake K, et.al., PLoS ONE 7(4): e34582 (2012). North America (athymic nude mice)
  276. Zhao S, et.al., Oncogenesis (2013) 2, e76. North America (athymic nude mice)
  277. Hernandez JL, et.al., PLoS ONE 8(9): e72480 (2013). Spain (athymic nude mice)
  278. Jager W, el.al., PLoS ONE 8(3): e59536 (2013). North America (athymic nude mice)
  279. Shin D.H, et.al., JNCI J Natl Cancer Inst (2013). North America (athymic nude mice)
  280. Venkatasubbarao K, et.al., Molecular Cancer 2013, 12:104. North America (athymic nude mice)
  281. Rybczynska A.A, el.al., J Nucl Med September 1, 2013. The Netherlands (athymic nude mice)
  282. Gholami S, et.al., Breast Cancer Research 2013, 15:R26. North America (athymic nude mice)
  283. Zins K, et.al., Mol. Sci. 2013, 14, 17958-17971. Germany (athymic nude mice)
  284. Benavente S, et.al., Clin Cancer Res March 1, 2009 15; 1585. North America (athymic nude mice)
  285. Verhoeff JJC, et.al., Radiation Oncology 2007, 2:38. The Netherlands (athymic nude mice)
  286. Alessandro GD, et.al., Cell Death and Disease (2013) 4, e773. Italy (C.B-17 SCID mice)
  287. Jiang J., et.al., Oncol Rep. 2012 October; 28(4): 1139–1145. North America (athymic nude mice)
  288. Koht HE., et.al., The Journal of Clinical investigation. Volume 122, number 3, March 2012. North America (athymic nude mice)
  289. Barok M., et.al., Breast Cancer Research 2011, 13:R46. The Netherlands (C.B-17 SCID mice)
  290. Thorner Ar., et.al., PLoS ONE 5(10)e13073. North America (athymic nude mice)
  291. Hamada K., et.al., Gynecologic Oncology 99 (2005) S159-S165. North America (athymic nude rats)
  292. Lheureux S., et.al. Transl Oncol. 2013 October; 6(5): 586–595. North America (athymic nude rats)
  293. Millar HJ., et.al., Cancer Epidemiol Biomarkers Prev August 2008 17; 2180. North America (athymic nude rats)
  294. Ayers GD., et.al., JUM June 1, 2010 vol. 29 no. 6 891-90. North America (athymic nude mice)
  295. Cyran CC., et.al., PLoS ONE 8(9): e76009. North America (athymic nude rats)
  296. Daigle SR., et.al., Blood 2013 122: 1017-1025. North America (athymic nude rats)
  297. Jafri SH., et al., Journal of Experimental & Clinical Cancer Research 2010 29:87. North America (C.B-17 SCID mice)
  298. Dingli D., et al., Blood 2003 102: 489-496. North America (C.B-17 SCID mice)
  299. Green TP., et.al., Molecular Oncology 3 (2009), 248-261. France (athymic nude mice)
  300. Kreider JW., at al., Cancer Research 39, 273-276, January 1979. North America (athymic nude mice)
  301. Welsch CW, et.al, JNCI J Natl Cancer Inst (1987) 78 (3): 557-565. North America (athymic nude mice)
  302. Park SI., et.al., Curr Protoc Pharmacol. 2010 December 1; 51: 14.15–14.15.27. North America (athymic nude mice)
  303. Fernandes MS., et.al., Clin Cancer Res August 1, 2009 15; 4847. North America (C.B-17 SCID mice)
  304. Mundra JJ., et.al, JPET August 2012 vol. 342 no. 2 273-287. North America (SCID mice)
  305. Peng KW., et.al., Blood, 1 October 2001. Vol. 98. Numb. 7. North America (C.B-17 SCID mice)
  306. Bhatia N., et.al., J Invest Dermatol. 2013 March ; 133(3): 759–767. North America (athymic nude mice)
  307. Mischek D., et.al., Journal of Biomedicine and Biotechnology, Volume 2009 (2009), Article ID 437284. Germany (SCID-beige mice)
  308. Harrell JC., et.al., Cancer Res September 15, 2006 66; 9308. North America (athymic nude mice)
  309. Kumar S., et.al., Am J Pathol. 2003 December; 163(6): 2531–2541. North America (athymic nude mice)
  310. Schafer JM., et.al., Clin Cancer Res November 2000 6; 4373. North America (athymic nude mice)
  311. Gottardis MM., et.al., J Steroid Biochem. 1988;30(1-6):311-4. North America (athymic nude mice)
  312. O’Regan RM., et. al., JNCI J Natl Cancer Inst (2002) 94 (4): 274-283. North America (athymic nude mice)
  313. Morrison MM., J Clin Invest. 2013;123(10):4329–4343. North America (athymic nude mice)
  314. Suhong Xiao, et.al., The Journal of Biological Chemistry, 287, 12559-12577. North America (athymic nude mice, beige-nude-xid mice, SHrNTM "Shorn" mice)